Acne vulgaris or acne is a common human skin disease, characterized by areas of skin with seborrhea (scaly red skin), comedones (blackheads and whiteheads), papules (pinheads), pustules (pimples) and possibly scarring. Acne affects mostly skin with the densest population of sebaceous follicles; these areas include the face, the upper part of the chest, and the back. Acne scars are the result of inflammation within the dermis brought on by acne. The scar is created by the wound trying to heal itself resulting in too much collagen in one spot.
Several different types of acne scar have been described:
- Ice pick scars: Deep pits, that are the most common and a classic sign of acne scarring.
- Box car scars: Angular scars that usually occur on the temple and cheeks, and can be either superficial or deep, these are similar to chickenpox scars.
- Rolling scars: Scars that give the skin a wave-like appearance.
- Hypertrophic scars: Thickened, or keloid scars.
A Phase II clinical study involved the use of ICX-RHY (VAVELTA) in acne scarring in a study conducted by Dr David Eccleston MB ChB, at the MediZen Clinic in Birmingham has been carried out. Subjects were followed out to 6 months post-treatment with the following results:
- The average satisfaction scores for the treatment at 6 months as assessed separately by both subjects and the investigator on a scale of 1 -10 (10 being the highest) were 6.8 and 6.3 respectively
- No serious adverse events have been observed and the product has been well tolerated